Analyzing LC-MS/MS data by spectral count and ion abundance: two case studies
نویسندگان
چکیده
منابع مشابه
Analyzing LC-MS/MS data by spectral count and ion abundance: two case studies.
In comparative proteomics studies, LC-MS/MS data is generally quantified using one or both of two measures: the spectral count, derived from the identification of MS/MS spectra, or some measure of ion abundance derived from the LC-MS data. Here we contrast the performance of these measures and show that ion abundance is the more sensitive. We also examine how the conclusions of a comparative an...
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ژورنال
عنوان ژورنال: Statistics and Its Interface
سال: 2012
ISSN: 1938-7989,1938-7997
DOI: 10.4310/sii.2012.v5.n1.a7